I Became the First Human Gene-Reprogrammer to Save my Late Wife, now, to Save my Son.

Marc Malone: Husband, Father, Self-Taught Scientist.

From Desperation to Discovery: How Love, Loss, and a Breakthrough Could Save a Billion Lives

My name is Marc. I’m a Widowed-father of 3 children who lost their mother. I’m not a professor. I don’t wear a lab coat. I had some scientific experience, but none in a deadly disease field. But I may have just opened up a safe and effective way to reprogram the human genome — and it all began with a fight to save my wife’s life.

She was diagnosed with one of the deadliest forms of cancer: triple-negative breast cancer (TNBC). The odds were against us. Every standard treatment failed. With odds of approximately 10% success rates in survival. So I did what no one expected — I taught myself molecular biology, pharmacology, and genetics. I dove headfirst into the science, fueled by desperation, love, and the refusal to accept that there was no hope.

Using a novel combination of FDA-approved compounds, nutraceuticals, and metabolic modulation, I reprogrammed her gene expression — turning off cancer stem cells, reactivating silenced hormone receptors (ESR1/PGR), and triggering a ~70% tumor reduction with zero toxicity. No AI. No technology. No gene editing. No radiation. Just pure biochemical intervention. This wasn’t a fluke. It was the first documented case of human epigenetic reprogramming restoring nonfunctional genes without altering DNA. I have mapped out an entirely novel, original and fully replicable formula of how to safely achieve this metabolic-genetic reprogramming so we can build upon it with further studies.

But our time ran out. Despite no conventional treatments regressing the disease, I regressed it twice, but had to learn (oncology, genetics, molecular biology) as her tumors were growing an abominable 1cm a week (for contrast, the average breast cancer tumor grows 1cm in 17 months). She was dying right in front of me, and our 3 children–and I was widowed with them aged 3 and under when she died in my arms. 2 of my 3 children are severely Autistic, my youngest daughter Skye, and my oldest, Arran. So I was alone to raise 2 toddlers and a baby, 2 of which had serious disabilities.

Now, the mission continues — for my son.

He carries hundreds of high-risk mutations. He has profound Autism, cognitive disability, with mutations awaiting to emerge in neurodegeneration, and cancer — so many hundreds of cancer – all written into his code. Doctors see inevitability. I see hope. Because what worked for her, with refinement, could work for him — and for millions more.

This isn't just about one boy, or one family. Over 1 billion people live with conditions rooted in gene silencing and epigenetic dysfunction. From cancer to Alzheimer’s, autism to autoimmunity — we’ve been treating symptoms while the genetic light switch stays off.

I am the only documented scientist in history to have a found a way to turn the genes back on. But we have to do so much more in research, dedication and safety evaluation before knowing for sure if this will save him, reverse Skye’s severe Autism as well, and hopefully help the Billion fellow humans in desperate need.

I am the only sole designer of a cancer treatment that is also epigenetic in the world (co-authors provided clinical review) and we published the first paper showing that global epigenetic reprogramming — via biochemical-metabolic-genetic induction, not gene editing — is not only possible, but clinically effective and safe. It’s real. It’s human-tested. And it could change medicine forever.

I wasn’t supposed to be the one to do this. It was supposed to be an ivy-league scholar with a trust fund and perfect academic record – not a boy who grew up in poverty, in government housing, who lost his father at 7, his mother chronically sick at 10, lost his brother at 21, and then his wife and the mother of the home at 32. I formulated the only human genetic reprogramming treatment–and also cancer reducing treatment–in our basement at home in desperation. The rules of biology were cracked open by grief-stricken hands. I’d rather Jillian be alive than change the world. But watching my son struggle through his life and then die young is unacceptable. Watching millions upon millions of others suffer like us, is unacceptable. So I hope you will join me, support me, and help me, save my family from more disability & disease, more loss, and maybe, just maybe, we can help that Billion people as well. I have seen the genetic results of reprogramming in real-time, so I know, impossible is not really impossible, and lacking hope is not a luxury I have. That many of us have.

I have to shoutout the doctors and nurses I worked with along the way, and the scientists who came before me. Without so much heavy research already being done in labs across the world, I wouldn’t have been able to do what I have done. I stand on their shoulders.

Airmid is only a name right now, I still work a 9-5 job, but the aspiration is we will build it into bioscientific brilliance and finish the work that started with tragedy, so it ends with joy.

My late wife gave me the understanding and the proof that can lead to saving my son, and he can lead to saving so many others. Save the boy, save the world.

I appreciate you,

Marc.